Molecular Therapy-Methods & Clinical Development

英文简介

Molecular TherapyMolecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide-, protein-, oligonucleotide-, and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Molecular Therapy is dedicated to promoting the sciences in genetics, medicine, and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy''s 2015 impact factor is 6.938.Molecular Therapy — Methods & Clinical DevelopmentsThe aim of Molecular Therapy—Methods & Clinical Development is to build upon the success of Molecular Therapy in publishing important peer-reviewed methods and procedures, as well as translational advances in the broad array of fields under the molecular therapy umbrella.Topics of particular interest within the journal''s scope include:Gene vector engineering and productionMethods for targeted genome editing and engineeringMethods and technology development for cell reprogramming and directed differentiation of pluripotent cellsMethods for gene and cell vector deliveryDevelopment of biomaterials and nanoparticles for applications in gene and cell therapy and regenerative medicineAnalysis of gene and cell vector biodistribution and trackingPharmacology/toxicology studies of new and next-generation vectorsMethods for cell isolation, engineering, culture, expansion, and transplantationCell processing, storage, and banking for therapeutic applicationPreclinical and QC/QA assay developmentTranslational and clinical scale-up and Good Manufacturing procedures and process developmentClinical protocol developmentComputational and bioinformatic methods for analysis, modeling, or visualization of biological dataNegotiating the regulatory approval process and obtaining such approval for clinical trials

中文简介

分子治疗《分子疗法》杂志是基因转移、载体开发与设计、干细胞操作、基因、肽、蛋白、寡核苷酸的开发、细胞疗法、疫苗开发、临床前目标验证、安全性/有效性研究和临床试验等领域的领先期刊。分子疗法致力于促进遗传学、医学和生物技术的科学发展。出版重要的同行评审研究和前沿评论和评论，该杂志继续吸引该领域的最佳材料。分子治疗2015年影响因子为6.938。分子治疗-方法和临床发展分子治疗方法和临床发展的目标是建立在分子治疗的成功之上，在分子治疗的保护伞下发表重要的同行评审的方法和程序，以及在广泛领域的转化进展。在期刊范围内特别感兴趣的主题包括:基因载体工程与生产靶向基因组编辑和工程方法多能细胞重编程和定向分化的方法与技术发展基因和细胞载体传递的方法用于基因、细胞治疗和再生医学的生物材料和纳米颗粒的开发分析基因和细胞载体的生物分布和跟踪新型和下一代载体的药理学/毒理学研究细胞分离、工程、培养、扩增和移植的方法细胞加工、储存和贮存，用于治疗临床前和QC/QA分析开发转化和临床推广以及良好的生产流程和工艺开发临床协议开发用于分析、建模或可视化生物数据的计算方法和生物信息学方法谈判监管审批流程，并获得临床试验的批准

影响因子趋势图