JOURNAL OF IMMUNOLOGICAL METHODS

英文简介

The Journal of Immunological Methods is devoted to covering techniques for: (1) Quantitating and detecting antibodies and/or antigens and haptens based on antigen-antibody interactions. (2) Fractionating and purifying immunoglobulins, lymphokines and other molecules of the immune system. (3) Isolating antigens and other substances important in immunological processes. (4) Labelling antigens and antibodies with radioactive and other markers. (5) Localizing antigens and/or antibodies in tissues and cells, in vivo or in vitro. (6) Detecting, enumerating and fractionating immunocompetent cells. (7) Assaying for cellular immunity. (8) Detecting cell-surface antigens by cell-cell interactions. (9) Initiating immunity and unresponsiveness. (10) Transplanting tissues. (11) Studying items closely related to immunity such as complement, reticuloendothelial system and others. In addition the journal will publish articles on novel methods for analysing the organization, structure and expression of genes for immunologically important molecules such as immunoglobulins, T cell receptors and accessory molecules involved in antigen recognition, processing and presentation. Submitted full length manuscripts should describe new methods of broad applicability to immunology and not simply the application of an established method to a particular substance - although papers describing such applications may be considered for publication as a short Technical Note The Recombinant Technology section will contain articles relating to modification by recombinant techniques of molecules of immunological interest; isolation of novel binding proteins by phage display; gene therapy; transfection; and expression. Immunology Protocols is a section providing detailed, step-by-step descriptions of new and established techniques in immunology. Articles on the molecular biological analysis of immunologically relevant receptor binding sites are also invited.

中文简介

《免疫学方法杂志》致力于涵盖以下技术:(1)基于抗原-抗体相互作用定量和检测抗体和/或抗原和半抗原。(2)分离纯化免疫球蛋白、淋巴因子等免疫系统分子。(3)分离免疫过程中重要的抗原等物质。(四)用放射性等标记物标记抗原、抗体。(5)在体内或体外的组织和细胞中定位抗原和/或抗体。(6)免疫感受性细胞的检测、计数和分离。(7)细胞免疫测定。(8)细胞-细胞相互作用检测细胞表面抗原。(9)启动免疫和无反应。(10)移植组织。(11)研究与免疫密切相关的补体、网状内皮系统等。此外，该杂志还将发表关于分析免疫重要分子(如免疫球蛋白、T细胞受体和参与抗原识别、处理和表达的辅助分子)基因的组织、结构和表达的新方法的文章。提交完整的手稿应该描述的新方法的广泛适用性免疫学并不是简单的应用程序的方法建立一个特定的物质——尽管论文描述这样的应用程序可以考虑发表一个简短的技术注意重组技术部分将包含有关修改文章通过重组技术的分子免疫学的兴趣;噬菌体显示技术分离新型结合蛋白基因治疗;转染;和表达。免疫学协议是一节提供详细的，一步一步的描述新的和建立的免疫学技术。也欢迎有关免疫相关受体结合位点的分子生物学分析的文章。

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