JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

英文简介

The Journal of Biochemical and Molecular Toxicology is an international journal that contains original research papers rapid communications mini-reviews and book reviews all focusing on the molecular mechanisms of action and detoxication of exogenous and endogenous chemicals and toxic agents. The scope includes effects on the organism at all stages of development on organ systems tissues and cells as well as on enzymes receptors hormones and genes. The biochemical and molecular aspects of uptake transport storage excretion lactivation and detoxication of drugs agricultural industrial and environmental chemicals natural products and food additives are all subjects suitable for publication. Of particular interest are aspects of molecular biology related to biochemical toxicology. These include studies of the expression of genes related to detoxication and activation enzymes toxicants with modes of action involving effects on nucleic acids gene expression and protein synthesis and the toxicity of products derived from biotechnology. Given the rapid development of the field of toxicology during the last few decades and the fundamental importance of biochemical mechanisms in all aspects of toxicology the Journal of Biochemical and Molecular Toxicology is of interest not only to active investigators in the field but to many other scientists. These include other biochemists molecular biologists and toxicologists involved in industrial and contract research and testing laboratories and those involved in legal and regulatory work related to toxic chemicals. The Journal of Biochemical and Molecular Toxicology is published bimonthly with one volume of 6 issues per calendar year.

中文简介

《生物化学和分子毒理学杂志》是一本国际性期刊，包含原始研究论文、快速通讯、小评论和书评，所有这些都集中在外生和内源性化学物质以及有毒物质的分子作用机制和解毒作用上。这一范围包括在器官系统、组织和细胞发育的各个阶段对机体的影响，以及对酶受体、激素和基因的影响。药物、农业、工业和环境化学品、天然产品和食品添加剂的吸收、运输、储存、排泄、发酵和解毒的生化和分子方面均适合发表。特别感兴趣的是与生化毒理学有关的分子生物学方面。这些研究包括与解毒和活化酶有关的基因表达和毒性因子的研究，其作用方式涉及对核酸基因表达和蛋白质合成的影响以及生物技术产品的毒性。鉴于毒理学领域在过去几十年中的快速发展以及生物化学机制在毒理学各个方面的基本重要性，《生物化学和分子毒理学杂志》不仅对该领域的活跃研究者感兴趣，而且对许多其他科学家也感兴趣。其中包括其他生物化学家、分子生物学家、从事工业和合同研究和测试实验室的毒理学家，以及从事与有毒化学品有关的法律和监管工作的人。《生化与分子毒理学杂志》每两个月出版一期，每日历年出版6期。

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