Future Medicinal Chemistry

英文简介

Medicinal chemistry has evolved rapidly into a highly interdisciplinary field, enriched by the collaborative efforts of experts from a wide spectrum of specialist areas, from chemoinformaticians and physical chemists to molecular biologists and pharmacologists. Future Medicinal Chemistry provides a monthly point of access to commentary and debate for this ever-expanding and diversifying community. The journal showcases milestones in pharmaceutical R&D and features expert analysis of emerging research-from the identification of targets, through to the discovery, design, synthesis and evaluation of bioactive agents.There has never been more pressure to produce potent and safe compounds faster and more efficiently. Future Medicinal Chemistry offers a forum for the rapid publication of original research and critical reviews of the latest milestones in the field. Strong emphasis is placed on ensuring that the journal stimulates awareness of issues that are anticipated to play an increasingly central role in influencing the future direction of pharmaceutical chemistry. Where relevant, contributions are also actively encouraged on areas as diverse as biotechnology, enzymology, green chemistry, genomics, immunology, materials science, neglected diseases and orphan drugs, pharmacogenomics, proteomics and toxicology.Principal themes include:Drug discovery technologiesDesign and synthesis of novel lead compoundsComputational approaches to synthesis and modelingBiophysical techniques for structural characterizationOverviews of novel therapeutic strategies and emerging targetsDrug targeting and deliveryADME/Tox investigationsCommentary on science policy, economic and IP issuesIn addition to its core content of Reviews, Patent Reviews, Perspectives and Original Research, the journal also features enlightened commentary and opinion on topical areas of debate relevant to academia and industry, as well as conference reports, interviews and more.By remaining highly responsive to emerging themes, and providing in-depth analysis of agents of medicinal interest and therapeutic approaches, the journal will act as a valuable reference, not only for medicinal chemists, but for all those interested in the advancement of pharmaceutical science.The journal welcomes unsolicited article proposals.

中文简介

药物化学已迅速发展成为一个高度跨学科的领域，丰富了从化学信息学家和物理化学家到分子生物学家和药理学家的广泛专业领域的专家的合作努力。未来的药物化学每月为这个不断扩大和多样化的社区提供评论和辩论的机会。该杂志展示了药物研发的里程碑和新兴研究的专家分析——从目标的识别，到生物活性药物的发现、设计、合成和评估。没有比这更大的压力来更快、更有效地生产有效、安全的化合物。未来的药物化学提供了一个论坛，为快速出版的原始研究和批评的最新里程碑在该领域。重点放在确保该期刊激发人们对预期将在影响药物化学未来方向方面发挥越来越重要作用的问题的认识。在相关领域，还积极鼓励在生物技术、酶学、绿色化学、基因组学、免疫学、材料科学、被忽视疾病和孤儿药物、药物基因组学、蛋白质组学和毒理学等多方面作出贡献。主要的主题包括：药物发现技术；新型先导化合物的设计与合成；综合和建模的计算方法；结构表征的生物物理技术；综述新的治疗策略和新出现的靶点；药物靶向与给药；托克斯ADME /调查；对科学政策、经济和知识产权问题的评论。除了核心内容的审查，专利审查，观点和原创研究，该杂志还提供开明的评论和意见，对与学术界和工业界有关的辩论热点领域，以及会议报告，采访等。通过保持对新兴主题的高度反应，并提供深入的药物兴趣和治疗方法的分析，该杂志将作为一个有价值的参考，不仅对药物化学家，而且对所有对药物科学的进步感兴趣的人。该杂志欢迎不请自来的文章建议。

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