Epigenetics

英文简介

Epigenetics publishes peer-reviewed original research and review articles that provide an unprecedented forum where epigenetic mechanisms and their role in diverse biological processes can be revealed, shared, and discussed. Epigenetics research studies heritable changes in gene expression caused by mechanisms others than the modification of the DNA sequence. Epigenetics therefore plays critical roles in a variety of biological systems, diseases, and disciplines. Topics of interest include (but are not limited to):DNA methylationNucleosome positioning and modificationGene silencingImprintingNuclear reprogrammingChromatin remodelingNon-coding RNANon-histone chromosomal elementsDosage compensationNuclear organizationEpigenetic therapy and diagnosticsNutrition and environmental epigeneticsCancer epigeneticsNeuroepigeneticsCancer has been traditionally the main focus of epigenetic studies; however, recent data suggest that epigenetics plays critical roles in all basic processes of life. Our journal provides a platform for the communication of methodologies, hypotheses, experimental approaches, and diagnostic agents by researchers working in a variety of systems who are unraveling the epigenetic facets of their specific fields of interest.

中文简介

表观遗传学发表同行评议的原创研究和综述文章，提供了一个前所未有的论坛，在这里，表观遗传学机制及其在各种生物过程中的作用可以被揭示、共享和讨论。表观遗传学研究的是基因表达的可遗传变化，其机制并非DNA序列的修饰。因此，表观遗传学在各种生物系统、疾病和学科中发挥着关键作用。感兴趣的题目包括(但不限于):DNA甲基化核小体定位和修饰基因沉默印记核重编程染色质重塑非编码RNANon-histone染色体元素剂量补偿核组织表观遗传学治疗和诊断营养和环境表观遗传学癌症表观遗传学Neuroepigenetics癌症历来是表观遗传学研究的主要焦点;然而，最近的数据表明，表观遗传学在生命的所有基本过程中都扮演着重要的角色。我们的期刊提供了一个平台，让研究人员在不同的系统中交流方法、假设、实验方法和诊断试剂，这些系统正在揭示他们感兴趣的特定领域的表观遗传学方面。

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