BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

英文简介

BBA General Subjects accepts for submission either original, hypothesis-driven studies or reviews covering subjects in biochemistry and biophysics that are considered to have general interest for a wide audience. Manuscripts with interdisciplinary approaches are especially encouraged.Preferred topics include medically important biochemistry/biophysics research and emerging areas such as nanobiology (nanoparticles, nanotoxicology, nanomedicine), systems biology (genomics, proteomics, lipidomics, glycomics, bioinformatics based on experimental approaches), chemical biology (chemical compounds, drug mechanisms, synthesis of novel compounds, click chemistry), structural biology (crystallography, NMR, multimeric proteins, protein dynamics), novel complexes (pure natural compounds, synthetic compounds, protein complexes, nucleic acid derivatives), cellular signaling (receptor signaling, protein phosphorylation cascades, phosphatases, secondary messengers, transcription regulation, gene expression), glycobiology (sugar metabolites and metabolism, glycosylated proteins, membrane protein, glycosylation, glycomics), redox biology (redox switches, glutathione and thioredoxin systems, oxygen and nitrogen radical species, superoxide, hydrogen peroxide, hydroxyl radical, nitric oxide, peroxides, hypoxia, redox regulation of transcription factors), neurobiology (neuronal growth factors and nerve signaling, glial cells, autonomic and central nervous systems), stem cells (differentiation, stem cell isolation and cultivation, growth factors), imaging methodologies and mechanistic characterization of compounds having biochemical importance and general interest (drug leads, toxicants, nutrients, metabolites).Authors must provide a sentence at submission stating the reason that the work described in the manuscript has general significance and interest to a wide audience. Claims of novelty do not suffice. The author statement will be used as an aid in the reviewing process and will be included in the final version of the accepted paper to orient readers of BBA General Subjects.

中文简介

BBA一般受试者接受提交原始的、假设驱动的研究或评论，这些研究或评论涉及生物化学和生物物理领域的受试者，这些学科被认为对广泛的受众具有普遍兴趣。特别鼓励采用跨学科方法的手稿。首选主题包括医学上重要的生物化学/生物物理研究和新兴领域，如纳米生物学（纳米粒子、纳米毒理学、纳米医学）、系统生物学（基因组学、蛋白质组学、脂质组学、糖组学、基于实验方法的生物信息学）、化学生物学（化学化合物、药物机制、合成新的化合物，点击化学），结构生物学（结晶学，核磁共振，多聚蛋白质，蛋白质动力学），新的复合物（纯天然化合物，合成化合物，蛋白质复合物，核酸衍生物），细胞信号传导（受体信号，蛋白质磷酸化级联，磷酸酶，二级信使，转录调节因子糖化、基因表达）、糖生物学（糖代谢产物和代谢、糖基化蛋白、膜蛋白、糖基化、糖代谢）、氧化还原生物学（氧化还原开关、谷胱甘肽和硫氧还蛋白系统、氧和氮自由基物种、超氧化物、过氧化氢、羟基自由基、一氧化氮、过氧化物、缺氧、氧化还原调节转录因子）、神经生物学（神经元生长因子和神经信号传导、胶质细胞、自主神经和中枢神经系统）、干细胞（分化、干细胞分离和培养、生长因子）、具有生化重要性和一般意义的化合物的成像方法学和机械特性（药物先导），有毒物质，营养物质，代谢物）。作者必须在提交时提供一句话，说明原稿中描述的工作对广大读者具有普遍意义和兴趣的原因。声称新颖性还不够。作者声明将作为审查过程中的一个辅助，并将包括在接受的论文的最终版本中，以确定BBA一般主题的读者的方向。

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